Histology and Morphometry Core
The overall goal of the Histology and Morphometry Core is
- To provide a common facility and expertise for the broad spectrum of morphologic studies that may be required for interpretation of studies of various models of kidney disease and their response to interventions;
- To provide tissue samples from existing archival specimens from various mouse and rat kidney disease models that may be used for exploration and characterization of expression patterns of various novel target molecules; and
- To develop and enhance existing morphologic techniques to improve the ability of center investigators to localize specific molecules and tissue sections, and to interpret their significance based on the spatial localization and relationship to patterns of injury.
The Core provides protocols and literature realted to histology and morphology and maintains a dedicated, up to date and interactive renal immunohistochemistry database that will outline all of the available renal cell specific antibodies, their characteristics and associated staining protocols.
The Histology and Morphometry Core