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Dr Adriana Hung and et al's publication in Nature Genetics

October 9th 2018

Dr. Adriana Hung, Associate Professor of Medicine, Division of Nephrology, Vanderbilt University Medical Center and et al's publication

"Genetic analysis of over 1 million people identifies 535 new loci associated with blood pressure traits"  in Nature's Genetics

Abstract

High blood pressure is a highly heritable and modifiable risk factor for cardiovascular disease. We report the largest genetic association study of blood pressure traits (systolic, diastolic and pulse pressure) to date in over 1 million people of European ancestry. We identify 535 novel blood pressure loci that not only offer new biological insights into blood pressure regulation but also highlight shared genetic architecture between blood pressure and lifestyle exposures. Our findings identify new biological pathways for blood pressure regulation with potential for improved cardiovascular disease prevention in the future.

PMID:
30224653
DOI:
10.1038/s41588-018-0205-x

To read full article see below

http://www.nature.com/articles/s41588-018-0205-x